Haptoglobin / DyLight 488 / 9G10
Haptoglobin / DyLight 488 / 9G10
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-05144G (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | Haptoglobin | |
| Clone | 9G10 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 488 | |
| Target Species | Human | |
| Applications | ELISA | |
| Description | Optimal dilution of this antibody should be experimentally determined. |
About Haptoglobin and DyLight 488
| Haptoglobin | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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