Prothrombin / DyLight 488 / 5G9
Prothrombin / DyLight 488 / 5G9
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-05138G (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | Prothrombin | |
| Clone | 5G9 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 488 | |
| Target Species | Human | |
| Applications | WB, ELISA | |
| Description | Optimal dilution of this antibody should be experimentally determined. |
About Prothrombin and DyLight 488
| Prothrombin | This gene encodes the prothrombin protein (also known as coagulation factor II). This protein is proteolytically cleaved in multiple steps to form the activated serine protease thrombin. The activated thrombin enzyme plays an important role in thrombosis and hemostasis by converting fibrinogen to fibrin during blood clot formation, by stimulating platelet aggregation, and by activating additional coagulation factors. Thrombin also plays a role in cell proliferation, tissue repair, and angiogenesis as well as maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in this gene lead to various forms of thrombosis and dysprothrombinemia. Rapid increases in cytokine levels following coronavirus infections can dysregulate the coagulation cascade and produce thrombosis, compromised blood supply, and organ failure. [provided by RefSeq, May 2020] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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