Leptin / DyLight 650 / 3
Leptin / DyLight 650 / 3
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-21618C (View supplier product page) | |
| Size | 100 μl | |
| Price | $349.00 | |
| Antigen | Leptin | |
| Clone | 3 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 650 | |
| Target Species | Human | |
| Applications | IHC-P, ELISA |
About Leptin and DyLight 650
| Leptin | This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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