Urokinase / DyLight 405LS / U-16
Urokinase / DyLight 405LS / U-16
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-05160V3 (View supplier product page) | |
| Size | 100 μl | |
| Price | $419.00 | |
| Antigen | Urokinase | |
| Clone | U-16 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 405LS | |
| Target Species | Human | |
| Applications | WB, ELISA, IHC-Fr | |
| Description | Protein A purified |
About Urokinase and DyLight 405LS
| Urokinase | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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Citations
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