Nav1.5 / DyLight 405 / 4G8:1G7

Product Details
Supplier
Catalog #: NBP2-50527V (View supplier product page)
Size 100 μl
Price $299.00
Antigen Nav1.5
Clone 4G8:1G7
Host Mouse
Isotype IgM
Conjugate DyLight 405
Target Species Human
Applications WB, FC
About Nav1.5 and DyLight 405
Nav1.5 The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra