FluoroFinder

	Supplier
	Catalog #:	NBP2-48003V (View supplier product page)
	Size	100 μl
	Price	$399.00
	Antigen	p53
	Clone	TRP/816
	Host	Mouse
	Isotype	IgG2a
	Conjugate	DyLight 405
	Target Species	Human
	Applications	WB, FC, IHC-P
	Description	Protein A or G purified

	p53	This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
	DyLight 405	DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

p53 / DyLight 405 / TRP/816