CD8a / DyLight 755 / YTS 105.18
CD8a / DyLight 755 / YTS 105.18
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB200-578IR (View supplier product page) | |
| Size | 125 μl | |
| Price | $399.00 | |
| Antigen | CD8a | |
| Clone | YTS 105.18 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | DyLight 755 | |
| Target Species | Human, Mouse | |
| Applications | FC, IHC-Fr, ICC/IF, IHC |
About CD8a and DyLight 755
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
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