FluoroFinder

	Supplier
	Catalog #:	NBP2-44399 (View supplier product page)
	Size	100 μg
	Price	$329.00
	Antigen	PD-1
	Clone	SPM597
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	Unconjugated
	Target Species	Human
	Applications	FC, IF, IHC-P
	Description	Protein A or G purified -

	PD-1	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]