IL-13 / DyLight 405LS / PVM13-1
IL-13 / DyLight 405LS / PVM13-1
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-46605V3 (View supplier product page) | |
| Size | 50 μl | |
| Price | $319.00 | |
| Antigen | IL-13 | |
| Clone | PVM13-1 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 405LS | |
| Target Species | Human | |
| Applications | FC, ELISA | |
| Description | Affinity purified |
About IL-13 and DyLight 405LS
| IL-13 | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
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Citations
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