MUC-1 / 7C / Polyclonal
MUC-1 / 7C / Polyclonal
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-60046V2 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $399.00 | |
| Antigen | MUC-1 | |
| Clone | Polyclonal | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | 7C | |
| Target Species | Bovine, Equine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat | |
| Applications | ICC, IF, WB, IHC, IHC-P | |
| Description | Affinity purified |
About MUC-1 and 7C
| MUC-1 | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011] | |
|---|---|---|
| 7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |
Citations
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