FluoroFinder

	Supplier
	Catalog #:	FAB6298N (View supplier product page)
	Size	100 μg
	Price	$329.00
	Antigen	MUC-1
	Clone	604804
	Host	Mouse
	Isotype	IgG2b
	Conjugate	Alexa Fluor 700
	Target Species	Human
	Applications	FC
	Description	Protein A or G purified from hybridoma culture supernatant

	MUC-1	This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
	Alexa Fluor 700	Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.

	Additional Sources

MUC-1 / Alexa Fluor 700 / 604804