LAT / Alexa Fluor 488 / 661002
LAT / Alexa Fluor 488 / 661002
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | FAB63341G (View supplier product page) | |
| Size | 100 μg | |
| Price | $269.00 | |
| Antigen | LAT | |
| Clone | 661002 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Protein A or G purified from hybridoma culture supernatant |
About LAT and Alexa Fluor 488
| LAT | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Citations
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