IL-18 / Alexa Fluor 405 / 74801
IL-18 / Alexa Fluor 405 / 74801
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | IC646V (View supplier product page) | |
| Size | 100 μg | |
| Price | $389.00 | |
| Antigen | IL-18 | |
| Clone | 74801 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alexa Fluor 405 | |
| Target Species | Human | |
| Applications | Isotype Ctrl | |
| Description | Protein A or G purified from ascites |
About IL-18 and Alexa Fluor 405
| IL-18 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] | |
|---|---|---|
| Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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