CD130 / Alexa Fluor 405 / 125623
CD130 / Alexa Fluor 405 / 125623
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | FAB4681V (View supplier product page) | |
| Size | 100 μg | |
| Price | $359.00 | |
| Antigen | CD130 | |
| Clone | 125623 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Alexa Fluor 405 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Protein A or G purified from hybridoma culture supernatant |
About CD130 and Alexa Fluor 405
| CD130 | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] | |
|---|---|---|
| Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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