GM-CSF / Alexa Fluor 405 / 83308
GM-CSF / Alexa Fluor 405 / 83308
Product Details
Supplier | ||
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Catalog #: | IC5181V (View supplier product page) | |
Size | 100 μg | |
Price | $299.00 | |
Antigen | GM-CSF | |
Clone | 83308 | |
Host | Mouse | |
Isotype | IgG2b | |
Conjugate | Alexa Fluor 405 | |
Target Species | Rat | |
Applications | Isotype Ctrl | |
Description | Protein A or G purified from hybridoma culture supernatant |
About GM-CSF and Alexa Fluor 405
GM-CSF | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020] | |
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Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |