GM-CSF / Alexa Fluor 405 / 83308

Product Details
Supplier
Catalog #: IC5181V (View supplier product page)
Size 100 μg
Price $299.00
Antigen GM-CSF
Clone 83308
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 405
Target Species Rat
Applications Isotype Ctrl
Description Protein A or G purified from hybridoma culture supernatant
About GM-CSF and Alexa Fluor 405
GM-CSF The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra