Flt-3 / Alexa Fluor 700 / 113308
Flt-3 / Alexa Fluor 700 / 113308
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | FAB7681N (View supplier product page) | |
| Size | 100 μg | |
| Price | $329.00 | |
| Antigen | Flt-3 | |
| Clone | 113308 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Alexa Fluor 700 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Protein A or G purified from hybridoma culture supernatant |
About Flt-3 and Alexa Fluor 700
| Flt-3 | This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015] | |
|---|---|---|
| Alexa Fluor 700 | Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720. |
Citations
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