FluoroFinder

	Supplier
	Catalog #:	FAB3478V (View supplier product page)
	Size	100 μg
	Price	$359.00
	Antigen	CCR10
	Clone	314305
	Host	Rat
	Isotype	IgG2a
	Conjugate	Alexa Fluor 405
	Target Species	Human
	Applications	FC
	Description	Protein A or G purified from hybridoma culture supernatant

	CCR10	Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
	Alexa Fluor 405	Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

CCR10 / Alexa Fluor 405 / 314305