CD86 / Alexa Fluor 405 / GL-1
CD86 / Alexa Fluor 405 / GL-1
Product Details
Supplier | ||
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Catalog #: | FAB741V (View supplier product page) | |
Size | 100 μg | |
Price | $299.00 | |
Antigen | CD86 | |
Clone | GL-1 | |
Host | Rat | |
Isotype | IgG2a | |
Conjugate | Alexa Fluor 405 | |
Target Species | Mouse | |
Applications | FC | |
Description | Protein A or G purified from hybridoma culture supernatant |
About CD86 and Alexa Fluor 405
CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
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Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |