IL-21 R / APC / 152512
IL-21 R / APC / 152512
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | FAB9911A-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $169.00 | |
| Antigen | IL-21 R | |
| Clone | 152512 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | FC |
About IL-21 R and APC
| IL-21 R | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Images
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Detection of IL-21 R in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human IL-21 R APC-conjugated Monoclonal Antibody (Catalog # FAB9911A) and Mouse Anti-Human CD19 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB4867F). Quadrant markers were set based on control antibody staining (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins. |
Citations
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