FluoroFinder

	Supplier
	Catalog #:	NBP2-34434V2 (View supplier product page)
	Size	100 Tests
	Price	$369.00
	Antigen	p53
	Clone	SPM590
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	7C
	Target Species	Bovine, Human, Primate
	Applications	WB, ELISA, FC, IHC-Fr, IHC-P, IP, ICC, IF
	Description	Protein A purified

	p53	This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
	7C	7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry.

	Additional Sources

p53 / 7C / SPM590