CD305 Monoclonal / Fluorescein / 342219
CD305 Monoclonal / Fluorescein / 342219
Product Details
Supplier | ||
---|---|---|
Catalog #: | FAB2664F (View supplier product page) | |
Size | 100 Tests | |
Price | $249.00 | |
Antigen | CD305 | |
Clone | 342219 | |
Host | Mouse | |
Isotype | IgG2b | |
Conjugate | Fluorescein | |
Target Species | Human | |
Applications | FC |
About CD305 and Fluorescein
CD305 | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | |
---|---|---|
Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |