JPH3 / Unconjugated /
JPH3 / Unconjugated /
Product Details
| Supplier | ProSci | |
|---|---|---|
| Catalog #: | 61-445-400UL (View supplier product page) | |
| Size | 400 μl | |
| Price | $482.00 | |
| Antigen | JPH3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | Ig | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | WB, IHC-P | |
| Description | Junctophilin 3 Antibody |
About JPH3 and Purified
| JPH3 | Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2016] |
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Citations
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