NOD2 / Unconjugated /

Product Details
Supplier ProSci
Catalog #: 2511-0.02MG (View supplier product page)
Size 20 μg
Price $120.00
Antigen NOD2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, ICC, IF
Description NOD2 Antibody
About NOD2 and Purified
NOD2 This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra