ATP6V0C / Unconjugated /
ATP6V0C / Unconjugated /
Product Details
Supplier | ProSci | |
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Catalog #: | 16-566-50UL (View supplier product page) | |
Size | 50 μl | |
Price | $332.00 | |
Antigen | ATP6V0C | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Mouse, Rat | |
Applications | WB, IF | |
Description | ATP6V0C Antibody |
About ATP6V0C and Purified
ATP6V0C | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010] |
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