CD38 / V450 / HIT2
CD38 / V450 / HIT2
Product Details
| Supplier | ProSci | |
|---|---|---|
| Catalog #: | 76-749-25TESTS (View supplier product page) | |
| Size | 25 Tests | |
| Price | $272.00 | |
| Antigen | CD38 | |
| Clone | HIT2 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | V450 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD38 Antibody [HIT2] (Violet-450) |
About CD38 and V450
| CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | |
|---|---|---|
| V450 | V450 (Horizon V450) from BD Biosciences has an excitation peak at 406 nm and an emission peak at 450 nm. It is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), Vio®Blue® (Miltenyi Biotec), Alexa Fluor™ 405 (ThermoFisher Scientific), Cascade Blue® (ThermoFisher Scientific), Pacific Blue (ThermoFisher Scientific), and ATTO 425 (ATTO-Tec) |
Citations
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