Neurofilament Heavy 200kDa / PE / NF421
Neurofilament Heavy 200kDa / PE / NF421
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-33102PE (View supplier product page) | |
| Size | 100 μl | |
| Price | $399.00 | |
| Antigen | Neurofilament Heavy 200kDa | |
| Clone | NF421 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | PE | |
| Target Species | Chicken, Human, Mouse, Porcine, Rat | |
| Applications | FC, ELISA, IHC-Fr, IHC-P | |
| Description | Protein G purified |
About Neurofilament Heavy 200kDa and PE
| Neurofilament Heavy 200kDa | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
| Additional Sources |
|
|---|
