IKZF3 / Alexa Fluor 405 / 1D7
IKZF3 / Alexa Fluor 405 / 1D7
Product Details
Supplier | ||
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Catalog #: | H00022806-M02AF405 (View supplier product page) | |
Size | 100 Tests | |
Price | $429.00 | |
Antigen | IKZF3 | |
Clone | 1D7 | |
Host | Mouse | |
Isotype | IgG2b κ | |
Conjugate | Alexa Fluor 405 | |
Target Species | Human | |
Applications | IF, ICC | |
Description | IgG purified - |
About IKZF3 and Alexa Fluor 405
IKZF3 | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] | |
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Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |