Serotonin N-acetyltransferase / Alexa Fluor 700 /
Serotonin N-acetyltransferase / Alexa Fluor 700 /
Product Details
Supplier | ||
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Catalog #: | NB100-135AF700 (View supplier product page) | |
Size | 100 μl | |
Price | $379.00 | |
Antigen | Serotonin N-acetyltransferase | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 700 | |
Target Species | Bovine (Negative), Chicken (Negative), Human, Primate, Rat (Negative), Zebrafish (Negative) | |
Applications | WB, ICC/IF |
About Serotonin N-acetyltransferase and Alexa Fluor 700
Serotonin N-acetyltransferase | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] | |
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Alexa Fluor 700 | Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720. |