RNF111 / Alexa Fluor 700 / 1C4
RNF111 / Alexa Fluor 700 / 1C4
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00054778-M05AF700 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | RNF111 | |
| Clone | 1C4 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 700 | |
| Target Species | Human | |
| Applications | IF, WB, ICC | |
| Description | IgG purified - - |
About RNF111 and Alexa Fluor 700
| RNF111 | The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012] | |
|---|---|---|
| Alexa Fluor 700 | Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720. |
Citations
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