Complement Factor B / Alexa Fluor 700 / 014III-33.2.4.3
Complement Factor B / Alexa Fluor 700 / 014III-33.2.4.3
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-64343AF700 (View supplier product page) | |
| Size | 50 Tests | |
| Price | $279.00 | |
| Antigen | Complement Factor B | |
| Clone | 014III-33.2.4.3 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alexa Fluor 700 | |
| Target Species | Human | |
| Applications | WB, FC, IHC, Functional, ELISA, IHC-Fr | |
| Description | Protein A purified |
About Complement Factor B and Alexa Fluor 700
| Complement Factor B | This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Alexa Fluor 700 | Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720. |
Citations
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