CD35 / Alexa Fluor 594 / 7G6
CD35 / Alexa Fluor 594 / 7G6
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-52667AF594 (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | CD35 | |
| Clone | 7G6 | |
| Host | Rabbit | |
| Isotype | IgG κ | |
| Conjugate | Alexa Fluor 594 | |
| Target Species | Mouse | |
| Applications | WB, FC, IHC, IHC-Fr | |
| Description | Optimal dilution of this antibody should be experimentally determined. |
About CD35 and Alexa Fluor 594
| CD35 | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020] | |
|---|---|---|
| Alexa Fluor 594 | Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive. |
Citations
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