MRPL12 / Alexa Fluor 405 / 3B12-1A3

Product Details
Supplier
Catalog #: H00006182-M01AF405 (View supplier product page)
Size 100 Tests
Price $429.00
Antigen MRPL12
Clone 3B12-1A3
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 405
Target Species Human
Applications IF, WB, IHC, ICC
Description IgG purified - -
About MRPL12 and Alexa Fluor 405
MRPL12 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
Citations
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Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra