CD86 / Alexa Fluor 350 / GL-1

Product Details
Supplier
Catalog #: NBP2-30148AF350 (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD86
Clone GL-1
Host Rat
Isotype IgG2a κ
Conjugate Alexa Fluor 350
Target Species Human, Mouse
Applications FC, Knockout Validated
Description Optimal dilution of this antibody should be experimentally determined.
About CD86 and Alexa Fluor 350
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra