Dnmt3b / Alexa Fluor 700 / 52A1018
Dnmt3b / Alexa Fluor 700 / 52A1018
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-56514AF700 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $329.00 | |
| Antigen | Dnmt3b | |
| Clone | 52A1018 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Alexa Fluor 700 | |
| Target Species | Human, Mouse | |
| Applications | WB, ChIP, IHC-P, ICC, IF | |
| Description | Protein G purified |
About Dnmt3b and Alexa Fluor 700
| Dnmt3b | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] | |
|---|---|---|
| Alexa Fluor 700 | Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720. |
Citations
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