FluoroFinder

	Supplier
	Catalog #:	H00004176-M01AF700 (View supplier product page)
	Size	100 Tests
	Price	$429.00
	Antigen	MCM7
	Clone	6C2
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	Alexa Fluor 700
	Target Species	Human
	Applications	IF, WB, IHC, PLA, ICC
	Description	IgG purified Proximity Ligation Assay - -

	MCM7	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
	Alexa Fluor 700	Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.

	Additional Sources

MCM7 / Alexa Fluor 700 / 6C2