PUMA / Alexa Fluor 405 / RB1353-RB1354
PUMA / Alexa Fluor 405 / RB1353-RB1354
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-94183AF405 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $499.00 | |
| Antigen | PUMA | |
| Clone | RB1353-RB1354 | |
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | Alexa Fluor 405 | |
| Target Species | Human, Mouse | |
| Applications | WB, FC, IHC, IP | |
| Description | IgG purified |
About PUMA and Alexa Fluor 405
| PUMA | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] | |
|---|---|---|
| Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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