MRPL12 / Alexa Fluor 488 / 3B12-1A3

Product Details
Supplier
Catalog #: H00006182-M01AF488 (View supplier product page)
Size 100 Tests
Price $429.00
Antigen MRPL12
Clone 3B12-1A3
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 488
Target Species Human
Applications IF, WB, IHC, ICC
Description IgG purified - -
About MRPL12 and Alexa Fluor 488
MRPL12 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Citations
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Reviews & Ratings
Alexa Fluor 488 Excitation and Emission Spectra