WRN / Alexa Fluor 488 / 3C11
WRN / Alexa Fluor 488 / 3C11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00007486-M09AF488 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | WRN | |
| Clone | 3C11 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human | |
| Applications | IF, WB, ICC | |
| Description | IgG purified - - |
About WRN and Alexa Fluor 488
| WRN | This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Citations
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