p63 / DyLight 755 / 87C553
p63 / DyLight 755 / 87C553
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-56549IR (View supplier product page) | |
| Size | 100 Tests | |
| Price | $399.00 | |
| Antigen | p63 | |
| Clone | 87C553 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 755 | |
| Target Species | Human | |
| Applications | WB | |
| Description | Protein G purified |
About p63 and DyLight 755
| p63 | This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
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