CD11b / Alexa Fluor 647 / 3A33
CD11b / Alexa Fluor 647 / 3A33
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-27874AF647 (View supplier product page) | |
| Size | 500 Tests | |
| Price | $449.00 | |
| Antigen | CD11b | |
| Clone | 3A33 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Mouse | |
| Applications | FC, IP | |
| Description | IgG purified |
About CD11b and Alexa Fluor 647
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Citations
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