API5 / Alexa Fluor 488 / 1C2
API5 / Alexa Fluor 488 / 1C2
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00008539-M01AF488 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | API5 | |
| Clone | 1C2 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human | |
| Applications | IF, WB, IHC, ICC | |
| Description | Protein A purified - |
About API5 and Alexa Fluor 488
| API5 | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Citations
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