FluoroFinder

	Supplier
	Catalog #:	NBP1-97693AF647 (View supplier product page)
	Size	100 Tests
	Price	$349.00
	Antigen	Glypican 3
	Clone	A7L6
	Host	Rat
	Isotype	IgG2a
	Conjugate	Alexa Fluor 647
	Target Species	Bovine, Human, Mouse, Rat
	Applications	WB, IHC, IP, IHC-Fr, IHC-P, ICC, IF
	Description	Affinity purified

	Glypican 3	Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
	Alexa Fluor 647	Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.

	Additional Sources

Glypican 3 / Alexa Fluor 647 / A7L6