FluoroFinder

	Supplier
	Catalog #:	H00001827-M03AF647 (View supplier product page)
	Size	100 Tests
	Price	$429.00
	Antigen	RCAN1
	Clone	1B1
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	Alexa Fluor 647
	Target Species	Human
	Applications	ICC, WB
	Description	IgG purified -

	RCAN1	The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
	Alexa Fluor 647	Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.

	Additional Sources

RCAN1 / Alexa Fluor 647 / 1B1