Importin alpha 2 / Alexa Fluor 647 / 2A4-1B5

Product Details
Supplier
Catalog #: H00003836-M01AF647 (View supplier product page)
Size 100 Tests
Price $429.00
Antigen Importin alpha 2
Clone 2A4-1B5
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 647
Target Species Human, Rat
Applications ICC, WB, IHC
Description IgG purified - -
About Importin alpha 2 and Alexa Fluor 647
Importin alpha 2 The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra