OAS1 / Alexa Fluor 488 / 2D4
OAS1 / Alexa Fluor 488 / 2D4
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00004938-M01AF488 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | OAS1 | |
| Clone | 2D4 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human | |
| Applications | IF, IHC, IP, ICC | |
| Description | IgG purified - - |
About OAS1 and Alexa Fluor 488
| OAS1 | This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Citations
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