IL-21 R / Alexa Fluor 647 / 4A9
IL-21 R / Alexa Fluor 647 / 4A9
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-43356AF647 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $299.00 | |
| Antigen | IL-21 R | |
| Clone | 4A9 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Protein A or G purified |
About IL-21 R and Alexa Fluor 647
| IL-21 R | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Citations
| Additional Sources |
|
|---|
