Dnmt3b / 7C / 52A1018
Dnmt3b / 7C / 52A1018
Product Details
Supplier | ||
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Catalog #: | NB100-56514V2 (View supplier product page) | |
Size | 100 Tests | |
Price | $329.00 | |
Antigen | Dnmt3b | |
Clone | 52A1018 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | 7C | |
Target Species | Human, Mouse | |
Applications | WB, ChIP, IHC, IP, IHC-P, ICC, IF | |
Description | Protein G purified - |
About Dnmt3b and 7C
Dnmt3b | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] | |
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7C | 7C from Novus/ Bio-Techne is a fluorophore with an excitation peak at 423 nm and an emission peak at 499 nm. It is an alternative to V500 or AmCyan in Flow Cytometry. |