Dnmt3b / DyLight 650 / 52A1018
Dnmt3b / DyLight 650 / 52A1018
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-56514C (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | Dnmt3b | |
| Clone | 52A1018 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 650 | |
| Target Species | Human, Mouse | |
| Applications | WB, IHC-P, ICC/IF, FC, IHC-Fr | |
| Description | Protein G purified |
About Dnmt3b and DyLight 650
| Dnmt3b | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] | |
|---|---|---|
| DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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