DUSP5 / Alexa Fluor 488 / 2F3
DUSP5 / Alexa Fluor 488 / 2F3
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | H00001847-M04AF488 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | DUSP5 | |
| Clone | 2F3 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human, Rat | |
| Applications | ICC, WB | |
| Description | IgG purified - |
About DUSP5 and Alexa Fluor 488
| DUSP5 | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Citations
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