FluoroFinder

	Supplier
	Catalog #:	NB100-2294IR (View supplier product page)
	Size	50 Tests
	Price	$219.00
	Antigen	RBM8A
	Clone	4C4
	Host	Mouse
	Isotype	IgG2b
	Conjugate	DyLight 755
	Target Species	Human, Mouse
	Applications	WB, IP, ELISA, ICC, IF
	Description	IgG purified

	RBM8A	This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
	DyLight 755	DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.

	Additional Sources

RBM8A / DyLight 755 / 4C4